Release of cytokines induced by Salmonella typhimurium porins

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Inflammatory effects of Salmonella typhimurium porins.

The inflammatory activity of porins purified from Salmonella typhimurium has been investigated. Porins (0.3 to 30 micrograms) injected into the rat paw induced a dose-related edema that was not due to lipopolysaccharide contamination and did not appear to be dependent on the activation of the complement system. The edema induced by 30 micrograms of porins was comparable to that caused by 1 mg o...

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COMPARATIVE CHARACTERIZATION OF PORINS FROM SALMONELLA TYPHIO-901 AND SALMONELLA TYPHIMURIUM RA-30

Porins from Salmonella typhi 0-901 and Salmonella typhimurium Ra-30 were characterized and compared. The elution profile of porins from these salmonella species on Sepharose-48 and HPLC appear to be very similar. The findings were confirmed by the electrophoretic pattern which showed three types of porins, i.e. OmpC, OmpD and OmpF in both species. These porins appear to be similar, if not ...

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comparative characterization of porins from salmonella typhio-901 and salmonella typhimurium ra-30

porins from salmonella typhi 0-901 and salmonella typhimurium ra-30 were characterized and compared. the elution profile of porins from these salmonella species on sepharose-48 and hplc appear to be very similar. the findings were confirmed by the electrophoretic pattern which showed three types of porins, i.e. ompc, ompd and ompf in both species. these porins appear to be similar, if not ident...

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Proteomic Changes in Chicken Plasma Induced by Salmonella typhimurium Lipopolysaccharides

Lipopolysaccharides (LPS) are cell wall components of Gram-negative bacteria that produce inflammation and sickness in higher animals. The objective was to identify plasma proteomic changes in an avian model of inflammation. Chickens were treated with either saline or LPS, and blood was collected at 24 hours postinjection. The pooled plasma samples were depleted of high-abundant proteins and an...

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Inhibition of ROS and upregulation of inflammatory cytokines by FoxO3a promotes survival against Salmonella typhimurium

Virulent intracellular pathogens, such as the Salmonella species, engage numerous virulence factors to subvert host defence mechanisms to induce a chronic infection that leads to typhoid or exacerbation of other chronic inflammatory conditions. Here we show the role of the forkhead transcription factor FoxO3a during infection of mice with Salmonella typhimurium (ST). Although FoxO3a signalling ...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1993

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.61.1.155-161.1993